| Development of a human-tissue-like phantom for 3.0-T MRI. | |
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MedLine Citation:
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PMID: 22047398 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Purpose: A 3.0-T MRI phantom having human-tissue-equivalent relaxation times was developed.Methods: The ingredients of the phantom are carrageenan (for gelatinization), GdCl(3) (as a T(1)-relaxation modifier), agarose (as a T(2)-relaxation modifier), and NaN(3) (as an antiseptic agent). Numerous samples with varying concentrations of GdCl(3) and agarose were prepared, and T(1) and T(2) were measured using 3.0-T MRI.Results: Relaxation times of the phantom samples ranged from 395 to 2601 ms for T(1) values and 29 to 334 ms for T(2) values. Based on the measured results, empirical formulae were devised to express the relationships between the concentrations of relaxation modifiers and relaxation times.Conclusions: Adjustment of GdCl(3) and agarose concentrations allows arbitrary setting of relaxation times, and the creation of a phantom that can mimic relaxation times of human-tissue. Carrageenan is considered the most suitable as a gelling agent for an MRI phantom, as it permits the relatively easy and inexpensive production of a large phantom such as for the human torso, and which can be easily shaped with a knife. |
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Authors:
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Yusuke Ikemoto; Wataru Takao; Keisuke Yoshitomi; Seiichiro Ohno; Takashi Harimoto; Susumu Kanazawa; Koichi Shibuya; Masahiro Kuroda; Hirokazu Kato |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical physics Volume: 38 ISSN: 0094-2405 ISO Abbreviation: Med Phys Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0425746 Medline TA: Med Phys Country: United States |
Other Details:
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Languages: eng Pagination: 6336 Citation Subset: IM |
Affiliation:
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Department of Radiology, Okayama Kyokuto Hospital, Okayama, Okayama 703-8265, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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