| Development of human gastrointestinal functions: interaction of changes in diet composition, hormonal maturation, and fetal genetic programming. | |
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MedLine Citation:
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PMID: 6432871 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two aspects of the physiology of the developing gastrointestinal tract are discussed. The first one deals with functional peculiarities of the developing gastrointestinal tract. Examples are shown that less active function in the suckling (eg, low pepsin digestion in the newborn stomach) may actually give the suckling an advantage for another process. The existence of pH close to neutrality in the suckling's stomach enables "survival" of the milk and lingual lipases that are then "cooperating" with low pancreatic lipase known to be present in the sucklings. The other aspect discussed deals with the role of various factors involved in postnatal maturation of the gastrointestinal function. Using sucrase activity as an example, the important role and mutual interaction of fetal (genetic?) programming, dietary changes, and hormonal maturation are reviewed. |
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Authors:
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O Koldovský |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of the American College of Nutrition Volume: 3 ISSN: 0731-5724 ISO Abbreviation: J Am Coll Nutr Publication Date: 1984 |
Date Detail:
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Created Date: 1984-10-02 Completed Date: 1984-10-02 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 8215879 Medline TA: J Am Coll Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 131-8 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Diet* Dietary Fats / metabolism Dietary Proteins / metabolism Digestion Digestive System / embryology, growth & development* Digestive System Physiological Phenomena Gastrointestinal Hormones / physiology* Humans Hydrogen-Ion Concentration Infant Food* Infant Nutritional Physiological Phenomena Infant, Newborn Intestinal Absorption Lactose / metabolism Lipase / metabolism Sucrase / metabolism Sucrose / metabolism beta-Galactosidase / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Dietary Proteins; 0/Gastrointestinal Hormones; 57-50-1/Sucrose; 63-42-3/Lactose; EC 3.1.1.3/Lipase; EC 3.2.1.23/beta-Galactosidase; EC 3.2.1.48/Sucrase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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