Document Detail


Development of a homologous transformation system for Aspergillus aculeatus based on the sC gene encoding ATP-sulfurylase.
MedLine Citation:
PMID:  19420695     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A homologous transformation system was developed using the endogenous ATP-sulfurylase gene, AasC, as a selectable marker in Aspergillus aculeatus. Spontaneous mutation was proved to be beneficial in isolating AasC-deficient mutants. Molecular analysis of sC(+) transformants revealed that the frequency of single copy integration at ATP-sulfurylase locus was more than 40%.
Authors:
Hiromi Adachi; Shuji Tani; Shin Kanamasa; Jun-ichi Sumitani; Takashi Kawaguchi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-05-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  73     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-25     Completed Date:  2009-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  1197-9     Citation Subset:  IM    
Affiliation:
Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aspergillus / genetics*
Genetic Engineering / methods*
Genome
Mutation
Sulfate Adenylyltransferase / genetics*
Transformation, Genetic*
Chemical
Reg. No./Substance:
EC 2.7.7.4/Sulfate Adenylyltransferase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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