Document Detail

Development of gastroschisis as seen by MRI.
MedLine Citation:
PMID:  21105024     Owner:  NLM     Status:  Publisher    
OBJECTIVES:: To describe the MRI-morphology and fetal development of gastroschisis METHODS:: Twenty-seven fetal MRI studies of 24 fetuses [21-38 gestational weeks (GW), mean: 30.8 GW] with gastroschisis were retrospectively analysed. The extra- and intraabdominal position of the abdominal organs was assessed on T1-, T2-weighted and steady-state free-precession sequences with emphasis on the intraabdominal findings. RESULTS:: Third trimester fetuses (n = 16) showed a uniform morphology: the extracorporal bowel included jejunum, ileum and colon except for parts of the sigmoid and the rectum. Intraabdominally the stomach was in contact with the left-sided urinary bladder (15/16). Second trimester fetuses (n = 8) differed with respect to the amount of intraabdominal bowel and had longer sections of the colon and jejunum intraabdominally. Intrauterine follow-up (n = 3) demonstrated exteriorisation of these bowel segments. Three third trimester fetuses with gastroschisis complicated by small bowel obstruction, in addition to the dilated small bowel loops, had variable lengths of intraabdominal colon. CONCLUSIONS:: Fetal development of gastroschisis is a dynamic process lasting until birth. The typical morphology of gastroschisis changes from the second to the third trimester, since intraabdominal bowel becomes eventrated by the end of the second trimester. This process of eventration is stopped in case of intestinal stenosis/atresia caused by narrowing of the abdominal wall defect, resulting in different lengths of intraabdominal bowel. The time when this occurs may correlate with the amount of viable bowel in case of intestinal atresia. The presented concept can explain the findings in closing gastroschisis. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Peter C Brugger; Daniela Prayer
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-11-23
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  -     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Integrative Morphology Group, Centre for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
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