Document Detail


[Development of gamete intrafallopian transfer with preincubated preovulatory oocytes (new GIFT) and analysis of clinical data].
MedLine Citation:
PMID:  3209912     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We developed a new treatment, Gamete Intrafallopian Transfer with the preincubated oocyte (New GIFT) and applied this method to all kinds of infertility where the patient had at least one tube. We performed 114 New GIFTs and dealt with the factors which influenced the establishment of pregnancy. 1. The pregnancy rate was 37%/cycles (42/114), 42%/patients (42/100) and the abortion rate was 19% (8/42). These results show that the New GIFT was more efficient than the original GIFT. 2. The most important factor for the establishment of pregnancy among the semen parameters was sperm motility, especially at the time of insemination. The pregnancy rate increased as sperm motility became higher. The sperm count did not influence the pregnancy rate significantly except in severe cases of oligozoospermia. 3. The most important factor in oocyte assessment was the number of mature oocytes. The number of oocytes in the pregnant group was much more than that in the nonpregnant group, but the total number of follicles in the pregnant group was found to be from 3 to 7 follicles. No pregnancy occurred when the number of follicles was greater than 11. These results suggested that existence an optimum number of oocytes. Conditions of the corona-cumulus component complex closely related to the establishment of pregnancy. The pregnancy rate was about 60% when more than 2C (-) oocytes (almost all cumulus cells were dispersed) were transferred, but it was only 5% when only C (+) oocytes (hardly any cumulus cells were dispersed) were transferred. 4. The most effective luteal support regimen was the pill. The administration of progesterone induced a high percentage of abortions.
Authors:
A Tanaka; M Toeda; I Nagasawa; T Yamamoto; N Nakagata
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Nihon Sanka Fujinka Gakkai zasshi     Volume:  40     ISSN:  0300-9165     ISO Abbreviation:  Nippon Sanka Fujinka Gakkai Zasshi     Publication Date:  1988 Dec 
Date Detail:
Created Date:  1989-02-15     Completed Date:  1989-02-15     Revised Date:  2011-07-29    
Medline Journal Info:
Nlm Unique ID:  7505749     Medline TA:  Nihon Sanka Fujinka Gakkai Zasshi     Country:  JAPAN    
Other Details:
Languages:  jpn     Pagination:  1859-66     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Koshigaya City Hospital, Saitama.
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MeSH Terms
Descriptor/Qualifier:
Female
Follicular Phase
Gamete Intrafallopian Transfer*
Humans
Infertility / therapy
Male
Oocytes
Ovarian Follicle
Sperm Count
Sperm Motility

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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