Document Detail

Development of the epidermis in the newborn.
MedLine Citation:
PMID:  3697429     Owner:  NLM     Status:  MEDLINE    
Histological development of the epidermis was studied on skin samples from 169 infants (gestation 24-40 weeks, age up to 1 year). Gestation markedly influenced epidermal development. Before 30 weeks, the epidermis is thin, has few cell layers and a poorly formed stratum corneum, but by 34 weeks it has largely matured. Postnatal influence on epidermal development is marked in the preterm infant, so that histologically the epidermis of the most immature infant resembles that of a term infant by 2 weeks of age. These changes in histology exactly parallel the development of the barrier properties of newborn skin.
N J Evans; N Rutter
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biology of the neonate     Volume:  49     ISSN:  0006-3126     ISO Abbreviation:  Biol. Neonate     Publication Date:  1986  
Date Detail:
Created Date:  1986-06-03     Completed Date:  1986-06-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0247551     Medline TA:  Biol Neonate     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  74-80     Citation Subset:  IM    
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MeSH Terms
Epidermis / anatomy & histology,  physiology*
Gestational Age
Infant, Newborn*
Infant, Premature*
Skin / growth & development*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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