Document Detail


Development of a w/o/w emulsion for chemical peeling applications containing glycolic acid.
MedLine Citation:
PMID:  17256078     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Glycolic acid is a member of the AHA family, which occurs naturally in foods and has been used for centuries as a cutaneous rejuvenation treatment. It is used in many cosmetic products as an exfoliant and moisturizer. When glycolic acid is used in greater amounts, however, there are greater cosmetic benefits but also potential for skin irritation as far as burning increases. The aim of this work was to investigate the feasibility of a topical delivery system as a multiple emulsion combining glycolic acid, strontium nitrate, and dexpanthenol in order to optimize the acid's cosmetic properties and lowering its side effects.
Authors:
Gülgün Yener; Aida Baitokova
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of cosmetic science     Volume:  57     ISSN:  1525-7886     ISO Abbreviation:  J Cosmet Sci     Publication Date:    2006 Nov-Dec
Date Detail:
Created Date:  2007-01-26     Completed Date:  2007-03-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9814276     Medline TA:  J Cosmet Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  487-94     Citation Subset:  IM    
Affiliation:
Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Cosmetics Section, Beyazit 34116, Istanbul, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Adult
Chemexfoliation / methods*
Cosmetics / administration & dosage,  chemical synthesis,  chemistry*
Drug Delivery Systems
Emulsions / chemical synthesis,  chemistry
Glycolates / administration & dosage*,  adverse effects,  chemistry
Humans
Keratolytic Agents / administration & dosage*,  adverse effects,  chemistry
Nitrates / administration & dosage,  chemistry
Pantothenic Acid / administration & dosage,  adverse effects,  analogs & derivatives,  chemistry
Skin Care
Strontium / administration & dosage,  chemistry
Wound Healing / drug effects
Chemical
Reg. No./Substance:
0/Cosmetics; 0/Emulsions; 0/Glycolates; 0/Keratolytic Agents; 0/Nitrates; 10042-76-9/strontium nitrate; 62507-76-0/dexpanthenol; 7440-24-6/Strontium; 79-14-1/glycolic acid; 79-83-4/Pantothenic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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