| Development of diaper rash in the newborn. | |
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MedLine Citation:
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PMID: 10720989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diaper rash is a common infant malady. This study documents the earliest stages of rash in a cohort of 31 healthy term newborns over the first 28 days of life. The diaper area was evaluated using a standardized diaper rash grading scale. The anal, buttock, genital, intertriginous, waistband, and leg areas were assessed separately. At birth the average grade was 0.1 and none of the infants had specific features of advanced rash. Nineteen percent had dryness and/or slight redness. By day 7, 71% of infants had some features of skin compromise, giving rise to an overall grade of 0.6. Both the frequency and overall grade increased during postnatal weeks 2 and 3. Overall scores for days 21 and 28 were the same (1.1). The perianal area had the highest overall regional rash grade. Gender differences were present for the genital area only. These findings indicate that epidermal barrier breakdown is an uncommon finding at birth. Clinical signs of irritated skin in the diaper area develop progressively over the first postnatal month. A better understanding of the mechanisms conferring epidermal barrier protection at birth may be important for developing skin care products and practices to extend this protection later into life. |
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Authors:
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M O Visscher; R Chatterjee; K A Munson; D E Bare; S B Hoath |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pediatric dermatology Volume: 17 ISSN: 0736-8046 ISO Abbreviation: Pediatr Dermatol Publication Date: 2000 Jan-Feb |
Date Detail:
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Created Date: 2000-04-11 Completed Date: 2000-04-11 Revised Date: 2009-03-03 |
Medline Journal Info:
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Nlm Unique ID: 8406799 Medline TA: Pediatr Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 52-7 Citation Subset: IM |
Affiliation:
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Skin Sciences Institute, Children's Hospital Research Foundation, University of Cincinnati, Ohio, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diaper Rash
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diagnosis* Female Humans Infant, Newborn Male Severity of Illness Index |
| Grant Support | |
ID/Acronym/Agency:
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R01 NR03699/NR/NINR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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