Document Detail

Development of cost-effective biocompatible packaging for microelectronic devices.
MedLine Citation:
PMID:  22256116     Owner:  NLM     Status:  MEDLINE    
A cost-effective, miniaturized and biocompatible packaging method for medical devices is proposed, resulting in a small, soft and comfortable implantable package. Towards this end, the barrier materials and fabrication process for the individual die encapsulation are largely explored. We demonstrate that various common clean room materials are good candidates for preventing metal leaching into body. In accelerated tests at higher temperature, several conductive barrier materials are damaged by the test bio-fluid, suggesting insufficient resistance to body fluids in long term. Covering electrodes by noble metals will solve this problem. For metallization, noble metals as Pt are best candidates. CoO calculations showed that selective plating of Pt is more cost-effective than sputtering. To reduce the cost of a sputter process, Pt recycling is very important.
Karen Qian; Karl Malachowski; Paolo Fiorini; Dimitrios Velenis; Maaike Op de Beeck; Chris Van Hoof
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-05-31     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  7674-7     Citation Subset:  IM    
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MeSH Terms
Biocompatible Materials / economics*
Cell Survival / drug effects
Coculture Techniques
Cost-Benefit Analysis
Diffusion / drug effects
Electronics, Medical / instrumentation*
Microscopy, Electron, Scanning
Miniaturization / instrumentation*
Myocytes, Cardiac / cytology,  drug effects
Platinum / pharmacology
Product Packaging / economics*,  methods*
Reg. No./Substance:
0/Biocompatible Materials; 49DFR088MY/Platinum

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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