Document Detail


Development of congenital laryngeal atresias and clefts.
MedLine Citation:
PMID:  3408110     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Congenital supraglottic laryngeal obstruction still is being described as subglottic stenosis. There are three clearly defined types of congenital laryngeal atresia, which result from arrest at consecutive developmental stages. Type 1 consists of a supraglottic obstruction, absent vestibule, and stenotic infraglottis, and type 2 is a supraglottic obstruction that separates a shallow primitive vestibule above from a nonstenotic infraglottis. These two types usually are accompanied by other defects, many of them severe. In type 3, a perforated membrane partly obstructs the glottis. Arrest of the dorsal advance of the chondrifying cricoid before the ends meet to form the dorsal lamina results in a complete laryngeal cleft, and incomplete fusion of the ends may leave a notch and/or foramen within the lamina. Failure of the interarytenoid tissue to develop will produce a local cleft, and maldevelopment of the cricoid cartilage or infraglottic submucosa can result in true subglottic stenosis without supraglottic obstruction.
Authors:
H I Zaw-Tun
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of otology, rhinology, and laryngology     Volume:  97     ISSN:  0003-4894     ISO Abbreviation:  Ann. Otol. Rhinol. Laryngol.     Publication Date:    1988 Jul-Aug
Date Detail:
Created Date:  1988-09-09     Completed Date:  1988-09-09     Revised Date:  2006-05-15    
Medline Journal Info:
Nlm Unique ID:  0407300     Medline TA:  Ann Otol Rhinol Laryngol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  353-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Anatomy, University of Alberta, Edmonton, Canada.
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MeSH Terms
Descriptor/Qualifier:
Humans
Laryngeal Cartilages / abnormalities
Laryngostenosis / congenital*,  embryology
Larynx / abnormalities*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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