Document Detail

Development of comprehensive disease assessment in systemic vasculitis.
MedLine Citation:
PMID:  18372486     Owner:  NLM     Status:  MEDLINE    
The systemic vasculitides are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This article reviews and summarises the development and use of disease assessment tools for determining activity and damage in systemic vasculitis and reports ongoing initiatives for further development of disease assessment tools. A literature search was conducted using PubMed and reference lists for vasculitis, assessment, clinical trials, outcome and prognosis. The findings indicate that comprehensive disease assessment in vasculitis requires documentation of disease activity, chronic irreversible damage and impairment of function.
O Flossmann; P Bacon; K de Groot; D Jayne; N Rasmussen; P Seo; K Westman; R Luqmani
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  84     ISSN:  1469-0756     ISO Abbreviation:  Postgrad Med J     Publication Date:  2008 Mar 
Date Detail:
Created Date:  2008-03-28     Completed Date:  2008-06-16     Revised Date:  2009-10-22    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  143-52     Citation Subset:  IM    
Botnar Research Centre,University of Oxford, Oxford, UK.
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MeSH Terms
Clinical Trials as Topic
Cost of Illness
Decision Support Systems, Clinical
Quality of Life
Risk Assessment / methods
Vasculitis / diagnosis*

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