| Development of comprehensive disease assessment in systemic vasculitis. | |
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MedLine Citation:
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PMID: 18372486 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The systemic vasculitides are multisystem disorders with considerable mortality and morbidity and frequent relapses. In the absence of reliable serological markers, accurate clinical tools are required to assess disease activity and damage for treatment decisions, and for the performance of clinical trials. This article reviews and summarises the development and use of disease assessment tools for determining activity and damage in systemic vasculitis and reports ongoing initiatives for further development of disease assessment tools. A literature search was conducted using PubMed and reference lists for vasculitis, assessment, clinical trials, outcome and prognosis. The findings indicate that comprehensive disease assessment in vasculitis requires documentation of disease activity, chronic irreversible damage and impairment of function. |
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Authors:
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O Flossmann; P Bacon; K de Groot; D Jayne; N Rasmussen; P Seo; K Westman; R Luqmani |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Postgraduate medical journal Volume: 84 ISSN: 1469-0756 ISO Abbreviation: Postgrad Med J Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-03-28 Completed Date: 2008-06-16 Revised Date: 2009-10-22 |
Medline Journal Info:
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Nlm Unique ID: 0234135 Medline TA: Postgrad Med J Country: England |
Other Details:
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Languages: eng Pagination: 143-52 Citation Subset: IM |
Affiliation:
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Botnar Research Centre,University of Oxford, Oxford, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Clinical Trials as Topic Cost of Illness Decision Support Systems, Clinical Forecasting Humans Quality of Life Questionnaires Risk Assessment / methods Vasculitis / diagnosis* |
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