Document Detail

Development of a compact mock circulation system and a new flow-cell model for pulse spectrophotometry.
MedLine Citation:
PMID:  19162744     Owner:  NLM     Status:  MEDLINE    
We have developed an extremely compact mock circulation system. This system can simulate artery blood circulation and generate a pulse wave with a very small amount of blood. We were also able to measure the in vitro pulsatile optical density ratio (Phivt) using this system with a flow cell [1]. Results showed a difference between Phivt and the in vivo pulsatile optical density ratio (Phivi) for the same oxygen saturations. To explain this difference, we proposed a new flow-cell model that includes venous flow and arterial flow. Because these systems can simulate the in vivo environment with very accurately, they can be applied to various pulse spectrophotometry studies. Moreover, the required blood volume is very small so the system can evaluate artificial blood or artificial red cells at very low cost. Thus, this system can reduce the time and cost of developing new pulse photometry techniques and other medical equipment.
M Oura; N Kobayashi; S Takeda; K Iwasaki; M Umezu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2008     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2008  
Date Detail:
Created Date:  2009-02-16     Completed Date:  2009-05-07     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  670-3     Citation Subset:  IM    
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MeSH Terms
Arteries / physiology*
Biomimetic Materials*
Equipment Design
Equipment Failure Analysis / instrumentation*,  methods
Flow Injection Analysis / instrumentation*
Oximetry / instrumentation*,  methods*
Pulsatile Flow / physiology*
Spectrophotometry / instrumentation*,  methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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