| Development of the capacity to produce specific antibody to an ingested food antigen in the premature infant. | |
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MedLine Citation:
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PMID: 1159577 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Thirteen premature infants were given bovine serum albumin, a cow milk protein, by addition to their formula. Serum antibodies to BSA developed in three infants 36-38 weeks' gestation, confirming that exposure to the antigen in the gastrointestinal tract will immunize infants born after 36 or more weeks' gestation. Serum antibodies to BSA, however, were detected in only one of two infants of 35 weeks' and in none of eight infants of 30-34 weeks' gestation. The results show that the capacity to make specific antibodies to BSA develops around 35-36 weeks' gestation, despite the prior appearance of organized lymphoid tissue and independent of antigen exposure. |
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Authors:
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C H Rieger; R M Rothberg |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pediatrics Volume: 87 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 1975 Oct |
Date Detail:
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Created Date: 1975-11-26 Completed Date: 1975-11-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 515-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antibody Formation* Antibody Specificity* Antigens* Female Food Hypersensitivity / immunology Gestational Age Humans Immunoglobulin G / analysis Infant Food Infant, Newborn Infant, Premature* Male Serum Albumin, Bovine / immunology* Umbilical Cord / immunology |
| Chemical | |
Reg. No./Substance:
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0/Antigens; 0/Immunoglobulin G; 0/Serum Albumin, Bovine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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