Document Detail


Development of anaplastic ependymoma in Rasmussen's encephalitis: review of the literature and case report.
MedLine Citation:
PMID:  15928965     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Rasmussen's encephalitis (RE) is a form of chronic encephalitis presenting with intractable seizures and progressive neurological deficits in children. The occurrence of anaplastic ependymoma in a diagnosed case of RE has not been reported in the literature. CASE REPORT: We report an eight and a half year-old boy, a diagnosed case of RE, suffering from intractable right-sided focal seizures, who developed features of raised intracranial pressure during follow-up. Repeat imaging revealed left fronto-temporoparietal mass for which near-total decompression was done. Histopathology of the mass revealed anaplastic ependymoma. CONCLUSION: The etiology of such a co-existence or development of malignancy in a pre-existing RE is yet to be completely understood. Both these entities could have a common etiology of viral- or autoimmune-mediated process, but no definite conclusion can be drawn with all the literature available at the moment.
Authors:
Raj Kumar; Abrar Ahad Wani; Jaypal Reddy; Lily Pal; Sunil Pradhan
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2005-06-01
Journal Detail:
Title:  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery     Volume:  22     ISSN:  0256-7040     ISO Abbreviation:  Childs Nerv Syst     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-28     Completed Date:  2007-09-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503227     Medline TA:  Childs Nerv Syst     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  416-9     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, 226014, India. rajkumar@sgpgi.ac.in
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MeSH Terms
Descriptor/Qualifier:
Atrophy
Brain Neoplasms / complications,  pathology*,  surgery
Cerebral Cortex / pathology,  surgery
Child
Child, Preschool
Encephalitis / complications,  pathology*,  surgery
Ependymoma / complications,  pathology*,  surgery
Humans
Infant
Male
Tomography, X-Ray Computed

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