Document Detail


Development of PET radiopharmaceuticals and their clinical applications at the Positron Medical Center.
MedLine Citation:
PMID:  20590833     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Positron Medical Center has developed a large number of radiopharmaceuticals and 36 radiopharmaceuticals have been approved for clinical use for studying aging and geriatric diseases, especially brain functions. Positron emission tomography (PET) has been used to provide a highly advanced PET-based diagnosis. The current status of the development of radiopharmaceuticals, and representative clinical and methodological results are reviewed.
Authors:
Kiichi Ishiwata; Yuichi Kimura; Keiichi Oda; Kenji Ishii; Muneyuki Sakata; Keiichi Kawasaki; Tadashi Nariai; Yukihisa Suzuki; Kenji Ishibashi; Masahiro Mishina; Masaya Hashimoto; Masatomo Ishikawa; Jun Toyohara
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Geriatrics & gerontology international     Volume:  10 Suppl 1     ISSN:  1447-0594     ISO Abbreviation:  Geriatr Gerontol Int     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-01     Completed Date:  2010-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101135738     Medline TA:  Geriatr Gerontol Int     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  S180-96     Citation Subset:  IM    
Affiliation:
Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan. ishiwata@pet.tmig.or.jp
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MeSH Terms
Descriptor/Qualifier:
Alzheimer Disease / radionuclide imaging*
Brain / blood supply
Glucose / metabolism
Humans
Muscle, Skeletal / radionuclide imaging
Parkinsonian Disorders / radionuclide imaging
Positron-Emission Tomography*
Radiopharmaceuticals
Receptor, Adenosine A1 / physiology
Receptor, Adenosine A2A / physiology
Receptors, Purinergic P1 / physiology
Receptors, sigma / physiology
Regional Blood Flow
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 0/Receptor, Adenosine A1; 0/Receptor, Adenosine A2A; 0/Receptors, Purinergic P1; 0/Receptors, sigma; 50-99-7/Glucose

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