| Development of NanoSafety Forecasting System from the Viewpoint of Nanomaterial-protein Interaction. | |
| | |
MedLine Citation:
|
PMID: 21297363 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
With recent developments in nanotechnology, nanomaterials have been successfully employed in various industrial applications such as medicine and cosmetics. Nanomaterials demonstrate useful properties such as electronic reactivity and tissue permeability that are absent in micromaterials. Thus, it is anticipated that nanomaterials will be developed as innovative materials in medicine and the cosmetics industry. However, these innovative properties may be accompanied by unknown biological responses that could not have been detected by conventional toxicity assays. To promote industrial development and to establish an affluent society that enjoys only the benefits of nanomaterials, we urgently need to gather information on the properties and biological effects of nanomaterials, and to establish appropriate standard safety evaluation methods. We are therefore analyzing the association of nanomaterial interactions with macromolecules (proteins, DNA etc.) and biodistribution using nanosilicas (nSP) as a standard nanomaterial. The results of this study are useful for extrapolation to other nanomaterials and to establish practicable strategies for the development of prediction methods for nanomaterials. |
| | |
Authors:
|
Tomoaki Yoshikawa |
Related Documents
:
|
8705913 - Cma's clinical q&a discussion group offers corridor consultations on the internet. 21288703 - Radiotherapy planning in high-grade gliomas: a survey of current uk practice. 3925293 - A gene controlling segregation of the bacillus subtilis plasmid pc194. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan Volume: 131 ISSN: 0031-6903 ISO Abbreviation: Yakugaku Zasshi Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-02-07 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0413613 Medline TA: Yakugaku Zasshi Country: Japan |
Other Details:
|
Languages: eng Pagination: 209-13 Citation Subset: IM |
Affiliation:
|
Department of Toxicology and Safety Science, Graduate School of Pharmaceutical Sciences, Osaka University. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Transdermal penetration and biodistribution of nanomaterials and their acute toxicity in vivo.
Next Document: Safety Studies of Nanomaterials about Intracellular Distribution and Genotoxicity.