| The development of EERA: software for assessing rheumatic joint erosions. | |
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MedLine Citation:
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PMID: 19433035 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The principal aim of this study was to create a segmentation program, to be used by nonmusculoskeletal or junior fellows, that defines the bones in the metacarpophalangeal joint in a dynamic 3-dimensional image that will lead to higher inter-reader agreement of bone erosion scores. METHODS: The second to fifth metacarpal head and phalangeal bases of 15 participants were rated according to the Rheumatoid Arthritis Magnetic Resonance Imaging Scoring system by one trained and one untrained reader. Two comparisons were made. The first comparison was between the 2 readers using only the traditional 2-dimensional magnetic resonance image set. The second comparison was between the 2 readers, with the untrained reader using a custom segmentation program with traditional 2-dimensional magnetic resonance image set. RESULTS: The software marginally increased inter-reader reliability with the exception of the second metacarpal head, for which reliability was increased substantially. Future work will concentrate on improving image acquisition, better delineate erosions from surrounding bone oedema, and address methods to directly determine erosion volumes. CONCLUSIONS: Software designed to display dynamic 3-dimensional images enables a relatively untrained user to score the metacarpophalangeal joints in the hand for erosions equivalent to that produced by an expert using the manual methods. |
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Authors:
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Patrick D Emond; Abram Choi; John O'Neill; Jason Xie; Rick Adachi; Chris L Gordon |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes Volume: 60 ISSN: 0846-5371 ISO Abbreviation: Can Assoc Radiol J Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-05-12 Completed Date: 2009-07-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8812910 Medline TA: Can Assoc Radiol J Country: Canada |
Other Details:
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Languages: eng Pagination: 63-8 Citation Subset: IM |
Affiliation:
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St Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada. edmondpd@mcmaster.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Arthritis, Rheumatoid
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diagnosis*,
pathology Disease Progression Humans Image Processing, Computer-Assisted / methods Imaging, Three-Dimensional / methods Magnetic Resonance Imaging / methods Metacarpophalangeal Joint / pathology* Observer Variation Reproducibility of Results Software* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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