| Development of Australian Reference Ranges for the Left Fetal Modified Myocardial Performance Index and the Influence of Caliper Location on Time Interval Measurement. | |
| | |
MedLine Citation:
|
PMID: 22759698 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Objectives: To construct gestational age-adjusted reference ranges of the left fetal modified myocardial performance index (Mod-MPI) in the Australian population and assess the influence of valve click caliper position on constituent time intervals and the Mod-MPI. Methods: This is a prospective longitudinal study of 117 normal singleton fetuses undergoing 318 ultrasound scans at 4-6 weekly intervals between 18 and 38 weeks of gestation. The isovolumetric contraction time (ICT), isovolumetric relaxation time (IRT), and ejection time (ET) were measured at 3 different caliper positions in each fetus: beginning of the original valve clicks ('original'), beginning of the reflected valve clicks ('reflected'), and peak of valve clicks ('peak'). The Mod-MPI was calculated as (ICT + IRT)/ET. Results: The Mod-MPI increased throughout gestation with means ± SD of 0.42 ± 0.05 'reflected' and 'peak' versus 0.49 ± 0.03 'original' at 19 weeks, and means of 0.46 ± 0.05 'reflected and peak' versus 0.51 ± 0.08 'original' at 36 weeks. Throughout gestation, ICT remained fairly constant and IRT increased, while ET decreased with 'original' click and remained constant for 'reflected' and 'peak' clicks. A modest increase in Mod-MPI was seen with increasing fetal heart rate. Analysis of repeatability for the 3 methods showed the following ICCs: 'original', 0.797 (95% CI 0.762-0.829); 'reflected', 0.809 (95% CI 0.775-0.839), and 'peak', 0.799 (95% CI 0.764-0.831). Conclusions: Detailed exploration of the morphology of mitral and aortic valve closure and opening clicks shows how selection of different phases of these clicks may significantly influence the Mod-MPI. We recommend that the peak of the valve clicks be standardized between research groups. |
| | |
Authors:
|
N Meriki; A W Welsh |
Related Documents
:
|
9618808 - Pericardial substitution after cardiopulmonary bypass surgery: a trial of an absorbable... 3524488 - Addition of papaverine to cardioplegia does not reduce myocardial necrosis. 10395358 - Successful orthotopic pig heart transplantation from non-heart-beating donors. 22287688 - Approach to the cardiac autopsy. 20036018 - Left ventricular twist and untwist in aortic stenosis. 23369948 - Comparison of the efficacy of the cardiac hypothermia and normothermia to myocardial da... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-6-28 |
Journal Detail:
|
Title: Fetal diagnosis and therapy Volume: - ISSN: 1421-9964 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
|
Created Date: 2012-7-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
|
Department of Obstetrics and Gynaecology, King Saud University, Riyadh, Saudi Arabia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Erectile Dysfunction Is Not Independently Associated with Cardiovascular Death: Data from the Vitami...
Next Document: Compulsive carnival song whistling following cardiac arrest: a case study.