| Devastating presentations of regional enteritis (Crohn's disease): two reports of survival following severe multiple organ dysfunction syndrome. | |
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MedLine Citation:
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PMID: 15684801 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Regional enteritis may present in the setting of a variety of clinical symptoms. These symptoms range from mild to severe. METHODS: Here we describe two different presentations of regional enteritis (Crohn's disease): one in the setting of Clostridium perfringens sepsis and the second in association with hemolytic-uremic syndrome. Both presentations resulted in life-threatening multiple organ dysfunction syndrome. RESULTS: Following appropriate surgical management and intensive physiologic support, both patients recovered, despite a MODS-predicted risk of mortality of 100% and 91%, respectively. CONCLUSIONS: Fulminant presentations of regional enteritis of this magnitude are rare, and highlight the resolution of severe multiple organ dysfunction for each presentation. |
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Authors:
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Catherine J Grossman; Lynn J Hydo; John C L Wang; Mark Pochapin; Philip S Barie |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Surgical infections Volume: 5 ISSN: 1096-2964 ISO Abbreviation: Surg Infect (Larchmt) Publication Date: 2004 |
Date Detail:
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Created Date: 2005-02-01 Completed Date: 2005-03-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9815642 Medline TA: Surg Infect (Larchmt) Country: United States |
Other Details:
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Languages: eng Pagination: 301-7 Citation Subset: IM |
Affiliation:
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Department of Surgery, Division of Critical Care and Trauma, Weill Medical College of Cornell University, New York, New York, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-Bacterial Agents Blood Chemical Analysis Clostridium Infections / diagnosis, therapy* Combined Modality Therapy Critical Illness Crohn Disease / diagnosis*, therapy* Disease Progression Drug Therapy, Combination / therapeutic use Female Follow-Up Studies Humans Laparotomy / methods Male Multiple Organ Failure / diagnosis, therapy* Risk Assessment Systemic Inflammatory Response Syndrome / diagnosis*, therapy* Tomography, X-Ray Computed Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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