Document Detail


Detrimental Effects of Divalproex on Warfarin Therapy Following Mechanical Valve Replacement.
MedLine Citation:
PMID:  21859435     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract  Drug interaction between Warfarin and psychiatric agents may have important therapeutic effects for patients undergoing cardiac surgery. We present a case of a patient in whom concurrent treatment with Warfarin and valproic acid resulted in supratherapeutic international normalized ratio values. A discussion of the possible mechanisms for this interaction as well as a review of interactions between Warfarin and other psychiatric medications is the subject of this case report. (J Card Surg 2011;**:1-3).
Authors:
Ashwini Nadkarni; Mark Oldham; Mark Howard; Harold L Lazar; Isidore Berenbaum
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-22
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  -     ISSN:  1540-8191     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Wiley Periodicals, Inc.
Affiliation:
Department of Psychiatry Department of Cardiothoracic Surgery, The Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts.
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