Document Detail


Determination of vitamin B12 in infant formula and adult nutritionals by HPLC: First Action 2011.10.
MedLine Citation:
PMID:  22649912     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
During the "Standards Development and International Harmonization: AOAC INTERNATIONAL Mid-Year Meeting" held on June 29, 2011, an Expert Review Panel (ERP) reviewed the method "Determination of Vitamin B12 in Infant Formula and Adult Nutritionals by HPLC." Under the new pathway to Official Methods, the ERP adopted the method as Official First Action. The method is applicable to the determination of vitamin B12 in infant formula and adult nutritionals. Data showed an average overall intermediate precision of 6.64% RSD, an estimated quantitation limit of 0.8 microg/kg, and a detection limit of 0.2 microg/kg in prepared samples. The standard range of the method is 2 to 200 microg/L, which corresponds to an analytical range of 0.8 to 500 microg/kg.
Authors:
Karen Schimpf; Renee Spiegel; Linda Thompson; Dawn Dowell
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of AOAC International     Volume:  95     ISSN:  1060-3271     ISO Abbreviation:  J AOAC Int     Publication Date:    2012 Mar-Apr
Date Detail:
Created Date:  2012-06-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9215446     Medline TA:  J AOAC Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  313-8     Citation Subset:  IM    
Affiliation:
Abbott Laboratories, 3300 Stelzer Rd, Columbus, OH 43219, USA. karen.schimpf@abbott.com
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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