Document Detail


Determination of sodium monofluoroacetate (compound 1080) in tissues and baits as its benzyl ester by reaction-capillary gas chromatography.
MedLine Citation:
PMID:  3626525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A reaction-capillary gas-chromatographic procedure using photo-ionization (PID) or flame-ionization (FID) detection was developed for the determination of sodium monofluoroacetate (compound 1080), a pesticide, in tissues and baits. Fluoroacetic acid from tissue (1 g) and bait (10 g) extracts was first partitioned into ethyl acetate and then into 0.5 M benzyldimethylphenylammonium hydroxide. Benzylation was achieved by pyrolysis of the quaternary ammonium salt in the injection port. Chloroacetic acid was used as the internal standard. A linear relationship (r = 0.999) was observed between the peak area ratio of the substrate/internal standard and the fluoroacetic acid concentration. The detection limit for compound 1080 using the described analytical procedure, was 15 micrograms/kg with PID and 100 micrograms/kg with FID.
Authors:
J J Hoogenboom; C G Rammell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of analytical toxicology     Volume:  11     ISSN:  0146-4760     ISO Abbreviation:  J Anal Toxicol     Publication Date:    1987 Jul-Aug
Date Detail:
Created Date:  1987-09-29     Completed Date:  1987-09-29     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7705085     Medline TA:  J Anal Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  140-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Benzyl Compounds / analysis
Chromatography, Gas / methods*
Fluoroacetates / analysis*
Rodenticides / analysis*
Chemical
Reg. No./Substance:
0/Benzyl Compounds; 0/Fluoroacetates; 0/Rodenticides; 144-49-0/fluoroacetic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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