| Determination of serum level of myoglobin and plasma level of autoantibodies to myoglobin in patients with angina pectoris. | |
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MedLine Citation:
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PMID: 2465975 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The serum level of myoglobin (Mb) was determined in 11 male patients with chronic ischemic heart disease (angiographically studied) by the mean of an enzyme immunoassay (EIA). By a second EIA we could detect in all our patients autoantibodies (autoAB) to Mb. While the level of Mb in all cases was normal (less than 100 ng/ml) we found differences in the level of autoAB to Mb (normal value 90-100%). 7 patients with unstable Angina pectoris exhibited decreased levels of autoAB to Mb (65%). In 4 patients with stable Angina pectoris autoAB to Mb were 93%. The physiological role of the autoAB to Mb remains still unclear. The simultaneous determination of Mb and the autoAB to Mb may be helpful in differential diagnosis of stable and unstable Angina pectoris. |
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Authors:
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G Grunow; M Dikov; H Reimann; C Norden; G Jermolin |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Folia haematologica (Leipzig, Germany : 1928) Volume: 115 ISSN: 0323-4347 ISO Abbreviation: Folia Haematol. Int. Mag. Klin. Morphol. Blutforsch. Publication Date: 1988 |
Date Detail:
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Created Date: 1989-04-13 Completed Date: 1989-04-13 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374615 Medline TA: Folia Haematol Int Mag Klin Morphol Blutforsch Country: GERMANY, EAST |
Other Details:
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Languages: eng Pagination: 573-6 Citation Subset: IM |
Affiliation:
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Central Institute for Cardiovascular Research, Academy of Sciences of the GDR, Berlin. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Angina Pectoris / blood* Autoantibodies / analysis* Creatine Kinase / blood Humans Immunoenzyme Techniques Male Middle Aged Myoglobin / blood*, immunology |
| Chemical | |
Reg. No./Substance:
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0/Autoantibodies; 0/Myoglobin; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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