Document Detail


Determination of prostate cancer risk factors in Isfahan, Iran: a case-control study.
MedLine Citation:
PMID:  22482343     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: This study was conducted in order to determine the risk factors of prostate cancer in Isfahan, Iran.
METHODS: In this case-control study 95 cases of incident, pathologically confirmed PC and 95 controls were recruited. Odds ratios (OR) and the corresponding 95% confidence intervals (CIs) were estimated using conditional logistic regression models.
RESULTS: The risk of prostate cancer increased with increasing age (OR: 1.09, 95% CI: 1.04-1.13; p < 0.001). A positive family history of prostate cancer was also a significant risk factor (OR: 2.5, 95% CI: 1.1-2.9; p = 0.03). Increased dietary intake tomato sauce was associated with a significantly declined risk of prostate cancer (OR: 0.05, 95% CI: 0.01-0.40; p < 0.001). Prostate cancer risk was not affected by Smoking, alcohol consumption, history of vasectomy, diabetes mellitus, sexually transmitted diseases, and dietary garlic and fat intake.
CONCLUSIONS: We found that increased age and positive family history of prostate cancer could be considered as some potential risk factors of prostate cancer in the studied population. Moreover, a higher intake of tomato sauce was found to have a protective effect against prostate cancer. Key words: Prostate cancer, risk factor, Iran.
Authors:
Hamid Mazdak; Mehrdad Mazdak; Leila Jamali; Ammar Hassanzadeh Keshteli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicinski arhiv     Volume:  66     ISSN:  0350-199X     ISO Abbreviation:  Med Arh     Publication Date:  2012  
Date Detail:
Created Date:  2012-04-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400722     Medline TA:  Med Arh     Country:  Bosnia and Hercegovina    
Other Details:
Languages:  eng     Pagination:  45-8     Citation Subset:  IM    
Affiliation:
Department of Urology, Alzahra University Hospital Isfahan University of Medical Sciences, Isfahan, Iran.
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