Document Detail


Determination of pharmaceutical compounds in hospital effluents and their contribution to wastewater treatment works.
MedLine Citation:
PMID:  19336268     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A method was developed for the simultaneous determination of almost 40 pharmaceuticals; including antidepressants, non-steroidal anti-inflammatories, analgesics, hypolipidemics, alpha- and beta-blockers, an anti cancer drug, anti-fungal agents, an opiate, an antibiotic, an anti-coagulant, a diuretic, an anti-anginal and an anti-diabetic compound. This was used to assess the contribution of pharmaceuticals originating from hospital effluents to one of Oslo city's wastewater treatment works. Some pharmaceuticals were found to contribute to more of the wastewater loading than others. 11% of the propranolol entering the wastewater treatment works stems from hospital effluent, approximately 2% of the atenolol, carbemazepine, metaprolol and atorvastatin, and for several other compounds the contribution is less than 1%. This assessment shows that point sources discharges from hospitals typically make a small contribution to the overall pharmaceutical load when compared to municipal areas, however this varies from substance to substance and is not the case when a drug's use is primarily hospital based.
Authors:
Katherine H Langford; Kevin V Thomas
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-31
Journal Detail:
Title:  Environment international     Volume:  35     ISSN:  1873-6750     ISO Abbreviation:  Environ Int     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-05-11     Completed Date:  2009-07-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7807270     Medline TA:  Environ Int     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  766-70     Citation Subset:  IM    
Affiliation:
NIVA, Norwegian Institute for Water Research, Gaustadaleen 21, 0349 Oslo, Norway. kla@niva.no
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MeSH Terms
Descriptor/Qualifier:
Chromatography, Liquid
Environmental Remediation
Hospitals*
Mass Spectrometry
Medical Waste Disposal*
Pharmaceutical Preparations / analysis*
Waste Disposal, Fluid
Water Pollutants, Chemical / analysis*
Chemical
Reg. No./Substance:
0/Medical Waste Disposal; 0/Pharmaceutical Preparations; 0/Water Pollutants, Chemical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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