Document Detail

Determination of the partial pressure of halothane (or isoflurane) in blood.
MedLine Citation:
PMID:  4015939     Owner:  NLM     Status:  MEDLINE    
A gas chromatographic method is described for the direct quantitative determination of the partial pressure of halothane (or isoflurane) in blood as well as the blood-gas partition coefficient. A head space technique and a flame ionization detector were used. Standard blood was obtained by equilibrating patients' blood with known gas concentrations in a tonometer. Using an infra-red analyser to measure the halothane gas concentration in the tonometer and within the anaesthetic system allowed for the direct comparison of the partial pressure in blood to the partial pressure in the inspired gas. Technical problems associated with this procedure, and with comparable methods, are discussed.
A M Zbinden; F J Frei; B Funk; D A Thomson; D Westenskow
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  57     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-09-06     Completed Date:  1985-09-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  796-802     Citation Subset:  IM    
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MeSH Terms
Chromatography, Gas / methods
Flame Ionization
Halothane / blood*
Isoflurane / blood*
Methyl Ethers / blood*
Partial Pressure
Reg. No./Substance:
0/Methyl Ethers; 151-67-7/Halothane; 26675-46-7/Isoflurane

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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