Document Detail


Determination of parameters of left ventricular diastolic filling with pulsed Doppler echocardiography: comparison with cineangiography.
MedLine Citation:
PMID:  3971525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the relationship between Doppler-derived flow velocity through the mitral anulus and angiographic parameters of left ventricular filling, 30 patients were studied by two-dimensional echocardiography combined with pulsed Doppler echocardiography followed within 1 hr by left ventricular angiography. The average heart rate for each test was 69 beats/min. Doppler-derived parameters included: early peak diastolic velocity (E) and peak atrial velocity, peak filling rate computed as E X cross-sectional area of the mitral anulus derived from the annular diameter, normalized peak filling rate computed as peak filling rate divided by the left ventricular end-diastolic volume determined by two-dimensional echocardiography, and half filling fraction derived from the time-velocity integral of the Doppler-determined velocity curve. Frame-by-frame left ventricular volumes were obtained throughout diastole from single-plane cineangiograms. A volume-time curve with its derivative was generated by computer processing from which peak filling rate, normalized peak filling rate, and half filling fraction were measured. Morphologically, the Doppler-derived velocity profile resembled the derivative of the angiographic volume curve. In patients with reduced angiographic peak filling rates, early peak diastolic velocity was often decreased less than 45 cm/sec with a relative increase in peak atrial velocity resulting in an early peak diastolic velocity to peak atrial velocity ratio less than 1.0. There were no significant differences in mean values for peak filling rate, normalized peak filling rate, and half filling fraction by Doppler echocardiography vs angiography (296 vs 283 ml/sec, 1.9 vs 2.0 sec-1 and 0.55 vs 0.55, respectively).(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
R Rokey; L C Kuo; W A Zoghbi; M C Limacher; M A Quinones
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Circulation     Volume:  71     ISSN:  0009-7322     ISO Abbreviation:  Circulation     Publication Date:  1985 Mar 
Date Detail:
Created Date:  1985-03-26     Completed Date:  1985-03-26     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0147763     Medline TA:  Circulation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  543-50     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Blood Flow Velocity
Blood Pressure
Cardiac Output*
Cineangiography*
Coronary Circulation
Coronary Disease / diagnosis,  physiopathology
Echocardiography / methods*
Female
Heart / radiography
Heart Catheterization
Heart Rate
Humans
Male
Middle Aged
Mitral Valve / physiology
Myocardial Contraction
Stroke Volume*
Time Factors
Grant Support
ID/Acronym/Agency:
RR-00350/RR/NCRR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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