Document Detail


Determination of organic acids in wine by zone electrophoresis on a chip with conductivity detection.
MedLine Citation:
PMID:  16013816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An appropriate combination of separation mechanisms (simultaneous use of differences in pK values, host-guest complexations, and the ionic strength dependences of the actual ionic mobilities) provided zone electrophoresis (ZE) resolution of 22 organic and inorganic acids expected in wines on a polymethylmethacrylate (PMMA) chip with integrated conductivity detection. These separating conditions offered a framework for the ZE determination of organic acids responsible for some important organoleptic characteristics of wines (tartrate, malate, succinate, acetate, citrate, and lactate). The ZE procedure developed in this context is simple and rapid (ca. 10 minutes' analysis time), while affording reproducible migration and quantitation data for the acids. For example, 0.8-2.0% RSD values characterized the migration times of the acids for 25 repeated ZE runs with the same sample carried out in 5 days in the background electrolyte solution prepared freshly on a daily basis, while 3-5% RSD values were typical for the accompanying peak area data. The concentration ranges within which the acids of analytical interest could be determined in one ZE run covered all wine samples included in our study (100-400-fold sample dilutions were needed to work under the conditions corresponding to the validities of the calibration data). 90-110% recoveries of the acids as obtained repeatedly for one of the reference wine samples used in our experiments indicate a good predisposition of the present method to provide accurate analytical results. This statement also supports the results from the determination of the acids in reference wine samples with claimed concentrations of malic (five samples), tartaric (one sample), and lactic (one sample) acids.
Authors:
Marián Masár; Katarina Poliaková; Mariana Danková; Dusan Kaniansky; Bernd Stanislawski
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of separation science     Volume:  28     ISSN:  1615-9306     ISO Abbreviation:  J Sep Sci     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-07-14     Completed Date:  2005-07-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101088554     Medline TA:  J Sep Sci     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  905-14     Citation Subset:  IM    
Affiliation:
Department of Analytical Chemistry, Faculty of Natural Sciences, Comenius University, Mlynská Dolina CH-2, SK-84215 Bratislava, Slovakia.
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MeSH Terms
Descriptor/Qualifier:
Acids / analysis*
Electrophoresis, Capillary / methods*
Organic Chemicals / analysis*
Wine / analysis*
Chemical
Reg. No./Substance:
0/Acids; 0/Organic Chemicals

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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