Document Detail


Determination of nucleic acids based on the quenching effect on resonance light scattering of the Y(III)-1,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hexane-dione system.
MedLine Citation:
PMID:  16502393     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nucleic acids can quench resonance light scattering (RLS) intensity of the Y(III)-1,6-bi(1'-phenyl-3'-methyl-5'-pyrazolone-4'-)hexane-dione(BPMPHD) complex in the pH range 5.0-5.8. Under optimal conditions, there are linear relationships between the quenching of RLS and the concentration of nucleic acids in the range 6.3 x 10(-8)-2.1 x 10(-5) g/mL for fish sperm DNA (fsDNA), 1.2 x 10(-8)-5.0 x 10(-5) g/mL for calf thymus DNA (ctDNA) and 6.0 x 10(-8)-2.0 x 10(-5) g/mL for yeast RNA (yRNA). The detection limits (3 s) of fsDNA, ctDNA and yRNA are 0.7 ng/mL, 3.8 ng/mL and 4.2 ng/mL, respectively.
Authors:
Xia Wu; Jing He Yang; Shuna Sun; Changying Guo; Dehuan Ran; Jinhua Zheng
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Luminescence : the journal of biological and chemical luminescence     Volume:  21     ISSN:  1522-7235     ISO Abbreviation:  Luminescence     Publication Date:    2006 May-Jun
Date Detail:
Created Date:  2006-05-22     Completed Date:  2006-08-30     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100889025     Medline TA:  Luminescence     Country:  England    
Other Details:
Languages:  eng     Pagination:  129-34     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 John Wiley & Sons, Ltd.
Affiliation:
Key Laboratory of Colloid and Interface Chemistry (Shandong University), Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Aldehydes / chemistry*
Animals
Cattle
DNA / analysis,  chemistry
Fishes
Hydrogen-Ion Concentration
Male
Nucleic Acids / analysis*,  chemistry*
Pyrazoles / chemistry*
RNA / analysis,  chemistry
Scattering, Radiation*
Sensitivity and Specificity
Spermatozoa / metabolism
Thymus Gland / metabolism
Yeasts / metabolism
Chemical
Reg. No./Substance:
0/1,6-bi(1'-phenyl-3'-methyl-5'-pyrazolon-4'-)hexanedione; 0/Aldehydes; 0/Nucleic Acids; 0/Pyrazoles; 63231-63-0/RNA; 9007-49-2/DNA; 91080-16-9/calf thymus DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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