| Determination of non-HDL cholesterol in diabetic and hypertensive patients. | |
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MedLine Citation:
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PMID: 20479581 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Recently, it has been suggested that non-high-density lipoprotein (non-HDL) cholesterol measure is a useful evaluation tool to assess heart disease death risk. The non-HDL cholesterol is defined as the value between total cholesterol and HDL - total cholesterol, and it involves the different fractions of lipoproteins: low-density lipoprotein, intermediate-density lipoprotein, and very low density lipoprotein, including highly atherogenic lipoproteins as very low density lipoprotein remnants. The purpose of this study was to compare the values of non-HDL cholesterol as a cardiovascular risk marker in a control population, and one diabetic and hypertensive. It was demonstrated that the mean values of non-HDL cholesterol in the diseased groups were higher than the values from the control group, whereas the low-density lipoprotein showed no marked difference in high-risk patients. Non-HDL cholesterol has shown to be a quick and simple way to estimate the risk of developing cardiovascular disease. |
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Authors:
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Freddy Contreras; Mary Lares; Jorge Castro; Manuel Velasco; Joselyn Rojas; Xavier Guerra; Maricarmen Chacín; Victoria Dowling; Valmore Bermúdez |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of therapeutics Volume: 17 ISSN: 1536-3686 ISO Abbreviation: Am J Ther Publication Date: 2010 May-Jun |
Date Detail:
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Created Date: 2010-05-18 Completed Date: 2010-08-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9441347 Medline TA: Am J Ther Country: United States |
Other Details:
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Languages: eng Pagination: 337-40 Citation Subset: IM |
Affiliation:
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Medicine School, Physiopathology Department, Universidad Central de Venezuela,Caracas, Venezuela. sicontreras@cantv.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Biological Markers / blood Cardiovascular Diseases / etiology Cholesterol / blood* Cholesterol, HDL / blood* Diabetes Mellitus, Type 2 / blood*, complications Female Humans Hypertension / blood*, complications Male Middle Aged Risk Factors Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Cholesterol, HDL; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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