Document Detail

Determination of lactic acid and pyruvic acid in serum and cerebrospinal fluid by ion-exclusion chromatography with a bulk acoustic wave detector.
MedLine Citation:
PMID:  8611947     Owner:  NLM     Status:  MEDLINE    
A chromatographic method base don a combination of ion-exclusion chromatography separation and bulk acoustic wave series piezoelectric quartz crystal detector quantification for the determination of pyruvic acid and lactic acid in serum and cerebrospinal fluid (CSF) was developed. The separation was carried out using a Shim-pak SCR-102H ion-exclusion column with phosphoric acid solution as eluent. The method shows an acceptable detection limit and anti-interference ability. Serum and CSF from healthy individuals and patient were analysed successfully.
P Chen; L H Nie; S Z Yao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of chromatography. B, Biomedical applications     Volume:  673     ISSN:  1572-6495     ISO Abbreviation:  J. Chromatogr. B, Biomed. Appl.     Publication Date:  1995 Nov 
Date Detail:
Created Date:  1996-06-03     Completed Date:  1996-06-03     Revised Date:  2007-10-16    
Medline Journal Info:
Nlm Unique ID:  9421796     Medline TA:  J Chromatogr B Biomed Appl     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  153-8     Citation Subset:  IM    
New Materials Research Institute, Hunan University, Changsha, China.
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MeSH Terms
Chromatography / methods*,  statistics & numerical data
Lactates / blood*,  cerebrospinal fluid*
Lactic Acid
Phosphoric Acids
Pyruvates / blood*,  cerebrospinal fluid*
Pyruvic Acid
Reference Values
Sensitivity and Specificity
Reg. No./Substance:
0/Lactates; 0/Phosphoric Acids; 0/Pyruvates; 0/Solutions; 127-17-3/Pyruvic Acid; 50-21-5/Lactic Acid; 7664-38-2/phosphoric acid

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