| Determination of halothane ED-50 in Mongolian gerbils (Meriones unguiculatus). | |
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MedLine Citation:
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PMID: 6716962 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effective dose-50 (ED-50) for halothane anesthesia was studied in 45 male Mongolian gerbils at age 12 weeks. Close control of circadian variation and animal temperature was maintained. Regression analysis for the percent of animals moving in response to a standard stimulus revealed an ED-50 of 1.32 volumes %, a concentration that approximates the ED-50 of the rat. |
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Authors:
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L M Thielhart; J A Reitan; R W Martucci |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Laboratory animal science Volume: 34 ISSN: 0023-6764 ISO Abbreviation: Lab. Anim. Sci. Publication Date: 1984 Feb |
Date Detail:
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Created Date: 1984-06-21 Completed Date: 1984-06-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 1266503 Medline TA: Lab Anim Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 75-6 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anesthesia, Inhalation
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veterinary* Animals Body Temperature Drug Tolerance Gerbillinae* Halothane / administration & dosage* Male Rats Regression Analysis |
| Chemical | |
Reg. No./Substance:
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151-67-7/Halothane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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