| Determination of gamma-aminobutyric acid by liquid chromatography with electrochemical detection. | |
| | |
MedLine Citation:
|
PMID: 7061649 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
gamma-Aminobutyric acid (GABA) has been determined in rat brain by derivatization with 2,4,6-trinitrobenzenesulfonic acid. The derivative and an internal standard, 2,4,6-trinitrophenyl-delta-aminovaleric acid, are extracted into toluene and separated by reversed-phase chromatography. Electrochemical reduction of these derivatives permits picomole measurements of GABA in microgram amounts of brain tissue. |
| | |
Authors:
|
W L Caudill; G P Houck; R M Wightman |
Related Documents
:
|
3818639 - Substrate stereospecificity and active site topography of gamma-aminobutyric acid amino... 1293019 - Effect of diethylcarbamazine on acetylcholine and gamma amino butyric acid in setaria d... 3393269 - A comparison of prodrug esters of nipecotic acid. 4029139 - Glutamic acid decarboxylase in tubules and glomeruli isolated from rat kidney cortex. 8838679 - Release of amino acids and related compounds from the adrenal equivalent and caudal vei... 5684199 - Activity of homocarnosine and other compounds against staphylococcal infections in mice. 15140949 - A universal evolutionary index for amino acid changes. 6473149 - Synthesis of vasoactive intestinal peptide (vip) via the mixed anhydride method. 22425999 - Endospore abundance, microbial growth and necromass turnover in deep sub-seafloor sedim... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Journal of chromatography Volume: 227 ISSN: 0021-9673 ISO Abbreviation: J. Chromatogr. Publication Date: 1982 Feb |
Date Detail:
|
Created Date: 1982-05-12 Completed Date: 1982-05-12 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0427043 Medline TA: J Chromatogr Country: NETHERLANDS |
Other Details:
|
Languages: eng Pagination: 331-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Brain Chemistry* Chromatography, Liquid / methods Electrochemistry Male Rats Rats, Inbred Strains gamma-Aminobutyric Acid / analysis* |
| Chemical | |
Reg. No./Substance:
|
56-12-2/gamma-Aminobutyric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Gas chromatographic method for the simultaneous determination of dopamine and norepinephrine metabol...
Next Document: Simplified procedure for the analysis of 3- and 4-hydroxyproline.