Document Detail


Determination of fluoroquinolones in blood by matrix solid-phase dispersion extraction and CE.
MedLine Citation:
PMID:  21374809     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A simple and rapid method for the determination of residues of four fluoroquinolones in blood samples was developed. The method was based on matrix solid-phase dispersion extraction followed by CE with ultraviolet detection. 1-Butyl-3-methylimidazolium tetrafluoroborate aqueous solution was used as the background electrolyte for the separation of fluoroquinolones. The average recoveries of the four fluoroquinolones at two spiked levels ranged from 54.0 to 86.4% for pig blood, and 45.4 to 79.9% for deer blood, with the relative standard deviations <9.45%. Detection limits for the four fluoroquinolones in blood sample ranged from 0.15 to 0.31 μg/mL.
Authors:
Dan Li; Qiuling Yang; Ziming Wang; Rui Su; Xu Xu; Hanqi Zhang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-4
Journal Detail:
Title:  Journal of separation science     Volume:  -     ISSN:  1615-9314     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-3-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101088554     Medline TA:  J Sep Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Department of Chemistry, Jilin University, Changchun, Jilin, P. R. China.
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