Document Detail


Determination of enantiomeric excess and concentration of unprotected amino acids, amines, amino alcohols, and carboxylic acids by competitive binding assays with a chiral scandium complex.
MedLine Citation:
PMID:  17031923     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A practical UV-vis sensing method for enantioselective microanalysis of unprotected amino acids, amines, amino alcohols, and carboxylic acids in aqueous solution has been developed. Both concentration and enantiomeric composition of a wide range of chiral substrates can be determined with high accuracy by two simple competitive binding assays using a scandium complex derived from 1,8-bis(3-(3',5'-dimethylphenyl)-9-acridyl)naphthalene N,N'-dioxide.
Authors:
Xuefeng Mei; Christian Wolf
Related Documents :
17266343 - Self-assembled monolayers of alkanoic acids on the native oxide surface of ss316l by so...
11539453 - Aldehydes in hydrothermal solution: standard partial molal thermodynamic properties an...
776443 - Enzymic analysis of bile acids.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  128     ISSN:  0002-7863     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-10-11     Completed Date:  2007-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  13326-7     Citation Subset:  IM    
Affiliation:
Department of Chemistry, Georgetown University, Washington, DC 20057, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amines / analysis*,  chemistry
Amino Acids / analysis*,  chemistry
Amino Alcohols / analysis*,  chemistry
Binding, Competitive
Biological Assay
Carboxylic Acids / analysis*,  chemistry
Molecular Structure
Organometallic Compounds / analysis*,  chemistry
Scandium / chemistry*
Spectrophotometry, Ultraviolet
Stereoisomerism
Valine / analysis,  chemistry
Chemical
Reg. No./Substance:
0/Amines; 0/Amino Acids; 0/Amino Alcohols; 0/Carboxylic Acids; 0/Organometallic Compounds; 7004-03-7/Valine; 7440-20-2/Scandium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Aggregation of the amphipathic peptides (AAKA)n into antiparallel beta-sheets.
Next Document:  Palladium-catalyzed asymmetric [3 + 2] trimethylenemethane cycloaddition reactions.