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Determination of cichoric acid content in dried press juice of purple coneflower (Echinacea purpurea) with capillary electrophoresis.
MedLine Citation:
PMID:  18970094     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Purple coneflower (Echinacea purpurea) is an immunostimulating drug, containing multiple substances. The most important in activity are polysaccharides, caffeic acid derivatives (cichoric acid), alkamides and glycoproteins. It is not clear yet, which substances are responsible for activity. Cichoric acid is an appropriate marker of the quality of E. purpurea containing product, because it has immune stimulatory effects and it is susceptible to degradation. In this work, an improved capillary electrophoresis method for determining cichoric acid in dried press juice from purple coneflower was developed. The optimal conditions were: electrophoretic buffer-75mM borate, pH 8.8; injection 20mbar for 20s; separation at 20kV; detection at 350nm, temperature 35 degrees C.
Authors:
Bronja Mancek; Samo Kreft
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Talanta     Volume:  66     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2008-10-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  1094-7     Citation Subset:  -    
Affiliation:
Krka, d.d., Novo mesto, Smarjeska cesta 6, 8501 Novo mesto, Slovenia.
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