| Determination of cardiac output by the Fick method, thermodilution, and acetylene rebreathing in pulmonary hypertension. | |
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MedLine Citation:
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PMID: 10430725 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Assessment of cardiac output is an important part of the management of patients with pulmonary hypertension. The accuracy of the thermodilution technique in patients with low cardiac output or severe tricuspid regurgitation has been questioned. To address this issue, we simultaneously compared 105 cardiac output measurements by the Fick method and thermodilution in 35 patients with pulmonary hypertension. Moreover, we evaluated the acetylene rebreathing technique, a noninvasive method of determining cardiac output. The mean difference +/- 95% limit of agreement between thermodilution and the Fick method was +0.01 +/- 1.1 L/min. The mean difference +/- 95% limit of agreement between acetylene rebreathing and the Fick method was -0.23 +/- 1.14 L/min. Neither the mean agreement nor the 95% limits of agreement of both thermodilution and acetylene rebreathing with the Fick method were affected by the presence of low cardiac output or severe tricuspid regurgitation. We conclude that thermodilution and acetylene rebreathing are useful tools for assessing cardiac output in patients with pulmonary hypertension, even in the presence of low cardiac output or severe tricuspid regurgitation. |
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Authors:
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M M Hoeper; R Maier; J Tongers; J Niedermeyer; J M Hohlfeld; M Hamm; H Fabel |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: American journal of respiratory and critical care medicine Volume: 160 ISSN: 1073-449X ISO Abbreviation: Am. J. Respir. Crit. Care Med. Publication Date: 1999 Aug |
Date Detail:
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Created Date: 1999-08-30 Completed Date: 1999-08-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9421642 Medline TA: Am J Respir Crit Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 535-41 Citation Subset: AIM; IM |
Affiliation:
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Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany. KMHoeper@AOL.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acetylene
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diagnostic use* Adult Aged Blood Gas Analysis* Cardiac Output / physiology Cardiac Output, Low / diagnosis*, physiopathology Female Humans Hypertension, Pulmonary / diagnosis*, physiopathology Male Middle Aged Prognosis Respiratory Mechanics / physiology Sensitivity and Specificity Thermodilution* Tricuspid Valve Insufficiency / diagnosis, physiopathology |
| Chemical | |
Reg. No./Substance:
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74-86-2/Acetylene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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