Document Detail


Determination of beta-carotene in plasma, blood cells and buccal mucosa by electrochemical detection.
MedLine Citation:
PMID:  1491599     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The beta-carotene concentrations in plasma, blood cells and buccal mucosal cells were determined by high-performance liquid chromatography with electrochemical detection. This method was 1,000 times more sensitive than the conventional spectrophotometric method. Polymorphonuclear cells and red blood cells had lower beta-carotene levels than the other cells. After oral administration of 580 mg/day of all-trans beta-carotene to human male volunteers for a week, the beta-carotene concentrations in all cell types increased at least several times above the original levels.
Authors:
T Murata; H Tamai; T Morinobu; M Manago; A Takenaka; H Takenaka; M Mino
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Lipids     Volume:  27     ISSN:  0024-4201     ISO Abbreviation:  Lipids     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1993-03-01     Completed Date:  1993-03-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0060450     Medline TA:  Lipids     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  840-3     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Osaka Medical College, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Platelets / chemistry
Carotenoids / analysis*,  blood*,  pharmacokinetics
Cheek
Chromatography, High Pressure Liquid / methods*
Electrochemistry
Erythrocytes / chemistry
Humans
Leukocytes, Mononuclear / chemistry
Male
Mouth Mucosa / chemistry*
Neutrophils / chemistry
beta Carotene
Chemical
Reg. No./Substance:
36-88-4/Carotenoids; 7235-40-7/beta Carotene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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