Document Detail


Determination of benorilate in pharmaceutical formulations and its metabolite in urine at carbon paste electrode modified by silver nanoparticles.
MedLine Citation:
PMID:  18970216     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Benorilate was determined by the differential pulse voltammetry (DPV) using a carbon paste electrode modified by silver nanoparticles in 1.25x10(-3)moll(-1) KH(2)PO(4) and Na(2)HPO(4) buffer solution (pH=6.88, 25 degrees C) .The anodic peak potential was +0.970V (versus SCE). A good linear relationship was realized between the anodic peak currents and benorilate concentrations in the range of 1.0x10(-7) to 2.5x10(-4)moll(-1) with the detection limit of 1.0x10(-8)moll(-1). The recovery was 95.2-103.6% with the relative standard deviation of 3.6% (n=9). The pharmaceutical preparations, benorilate tablets samples and its metabolite (salicylic acid) in urine were determined with the desirable results.
Authors:
Cheng Yin Wang; Xiao Ya Hu
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Publication Detail:
Type:  Journal Article     Date:  2005-04-18
Journal Detail:
Title:  Talanta     Volume:  67     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2008-10-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  625-33     Citation Subset:  -    
Affiliation:
Department of Chemistry and Chemical Engineering, Yangzhou University, 180 Siwangting lu, Yangzhou 225002, China.
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