Document Detail


Determination of the Maximal Lactate Steady State in Obese Zucker Rats.
MedLine Citation:
PMID:  22972243     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This study aims to identify the maximum lactate steady state (MLSS) in obese rats in order to provide a more effective tool in the exercise training prescription for this important animal model. To make such determination, obese (Zucker, n=5) (390.0±18.8 g) and lean (Wistar, n=5) (227.3±26.2 g) rats were studied. After adaptation of animals to treadmill, the MLSS was determined by using 3 different velocities (10 m.min - 1, 12.5 m.min - 1 and 15 m.min - 1 for Zucker and 15 m.min - 1, 20 m.min - 1 and 25 m.min - 1 for Wistar). The MLSS was defined as the highest blood lactate concentration that increased up to 1 mmol.L - 1 during constant exercise. In obese rats, the MLSS was found in a velocity considerably lower than in lean controls (12.5 m.min - 1 and 20 m.min - 1), respectively (p<0.05). Therefore, the identification of MLSS in obese Zucker rats is an important tool for exercise prescription and evaluation in obese rat models.
Authors:
J A Almeida; B A Petriz; C P C Gomes; L A O Rocha; R W Pereira; O L Franco
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-12
Journal Detail:
Title:  International journal of sports medicine     Volume:  -     ISSN:  1439-3964     ISO Abbreviation:  Int J Sports Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Physical Education, Catholic University of Brasilia, Taguatinga, Brazil.
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