| Determinants of sudden cardiac death in patients with persistent atrial fibrillation in the rate control versus electrical cardioversion (RACE) study. | |
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MedLine Citation:
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PMID: 16996876 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report evaluated the correlates of sudden cardiac and nonsudden cardiac death in patients with persistent atrial fibrillation randomized to rate or rhythm control in the RAte Control vs Electrical cardioversion (RACE) study. Sudden cardiac death was observed in 16 patients, 8 patients in each group. Previous myocardial infarction resulted in a 4.9-fold increased risk of sudden death (95% confidence interval 1.8 to 13.2). The use of beta blockers showed their protective nature (hazard ratio 0.2, 95% confidence interval 0.05 to 0.9). The randomized treatment strategy, heart rhythm during follow-up, use of antiarrhythmic drugs, and number of stroke risk factors were not associated with sudden cardiac death. In conclusion, the treatment of underlying disease, rather than the heart rhythm, seems essential to prevent mortality. |
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Authors:
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Vincent E Hagens; Michiel Rienstra; Dirk J Van Veldhuisen; Harry J G M Crijns; Isabelle C Van Gelder |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't Date: 2006-08-11 |
Journal Detail:
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Title: The American journal of cardiology Volume: 98 ISSN: 0002-9149 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2006 Oct |
Date Detail:
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Created Date: 2006-09-25 Completed Date: 2006-11-09 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 929-32 Citation Subset: AIM; IM |
Affiliation:
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Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use Aged Amiodarone / therapeutic use Anti-Arrhythmia Agents / therapeutic use* Atrial Fibrillation / mortality, therapy* Calcium Channel Blockers / therapeutic use Death, Sudden, Cardiac* Diabetes Mellitus / epidemiology Digitalis Glycosides / therapeutic use Electric Countershock* Fatigue / epidemiology Female Flecainide / therapeutic use Follow-Up Studies Humans Male Myocardial Infarction / epidemiology Netherlands / epidemiology Proportional Hazards Models Recurrence / prevention & control Risk Factors Sotalol / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Anti-Arrhythmia Agents; 0/Calcium Channel Blockers; 0/Digitalis Glycosides; 1951-25-3/Amiodarone; 3930-20-9/Sotalol; 54143-55-4/Flecainide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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