Document Detail

Determinants of pregnancy rate and obstetric outcome after laparoscopic myomectomy for infertility.
MedLine Citation:
PMID:  11476788     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the effect of myomectomy on infertility and to assess the factors influencing reproductive outcome. DESIGN: Retrospective study. SETTING: Tertiary care center. PATIENT(S): One hundred and three infertile women with uterine leiomyoma who had had infertility >2 years and a follow-up time >12 months were enrolled. Follow-up was complete for 88 patients, including 28 (31.8%) with primary infertility and 44 (50%) with unexplained infertility. The mean (+/-SD) age of the patients was 36.1 +/- 2.1 years. INTERVENTION(S): Laparoscopic myomectomy. MAIN OUTCOME MEASURE(S): Pregnancy rate according to patient and fibroid characteristics. RESULT(S): Forty-two patients became pregnant (40.7%). The mean (+/-SD) delay in conception was 7.5 +/- 2.6 months. Nearly 80% of the women conceived spontaneously. Of 44 pregnancies in 42 women, 36 live newborns were delivered. No dehiscence of uterine scar occurred. The pregnancy rate was significantly higher in women <35 years of age or <3 years of infertility. Women with unexplained infertility had higher pregnancy rate than did women with multifactorial infertility (P<.001). No difference was noted in pregnancy rates according to fibroid characteristics. CONCLUSION(S): Fertility and pregnancy after laparoscopic myomectomy depend primarily on patient age, duration of infertility before myomectomy, and existence of associated infertility factors.
L Dessolle; D Soriano; C Poncelet; J L Benifla; P Madelenat; E Daraï
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  76     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-07-30     Completed Date:  2001-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  370-4     Citation Subset:  IM    
Hôpital Hôtel-Dieu de Paris, Paris, France.
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MeSH Terms
Gynecologic Surgical Procedures / methods*
Infertility, Female / therapy*
Myometrium / surgery
Outcome Assessment (Health Care)*
Pregnancy Rate*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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