Document Detail

Determinants of a positive exercise test in patients admitted with acute non-infarct chest pain.
MedLine Citation:
PMID:  9829327     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: Some patients with suspected unstable angina show ischemia at the exercise treadmill test despite having been medically stabilized. The objective of this study was to determine clinical characteristics predicting a positive exercise treadmill test in patients with suspected unstable angina after medical stabilization. METHODS: In 885 hospitalized patients with medically stabilized unstable angina, the relationship between the result of the pre-discharge exercise treadmill test and clinical characteristics was studied. RESULTS: Mean age was 62+/-9 years and 668 (75%) were male. Exercise test was positive (chest pain and/or ST depression > or =1 mm) in 288 patients (33%). Univariate analysis showed the following associated with ischemia at the exercise test: male gender (56% vs. 20%, P<0.001 ), diabetes mellitus (41% vs. 31%, P=0.009), previous unstable angina (41% vs. 24%, P=0.001), previous stable angina (44% vs. 30%, P<0.001), previous coronary artery bypass grafting (43% vs. 31%, P=0.043), peripheral artery disease (45% vs. 31%) and progressive angina (55% vs. 31%, P<0.001). Multivariate analysis showed the following as independent predictors of ischemia: male gender (OR=2.25), diabetes (OR=4.12), previous unstable angina (OR=3.89), previous stable angina (OR=3.74) and progressive angina (OR=4.05). CONCLUSIONS: In patients with suspected unstable angina, after medical stabilization: (1) the exercise treadmill test is positive in one-third of cases; (2) male gender, diabetes, previous angina (unstable and stable) and progressive angina are independent predictors of ischemia.
R Moreno; J L Cantalapiedra; E López de Sá; A Ortega; J Fernández Portales; J Fernández-Bobadilla; J L López-Sendón; J L Delcán
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of cardiology     Volume:  66     ISSN:  0167-5273     ISO Abbreviation:  Int. J. Cardiol.     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1999-01-21     Completed Date:  1999-01-21     Revised Date:  2006-07-12    
Medline Journal Info:
Nlm Unique ID:  8200291     Medline TA:  Int J Cardiol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  147-51     Citation Subset:  IM    
Cardiology Department, Hospital Gregorio Marañón, Doctor Esquerdo, Madrid, Spain.
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MeSH Terms
Acute Disease
Angina, Unstable / diagnosis*
Exercise Test*
Middle Aged
Predictive Value of Tests

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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