Document Detail

Determinants of organ malfunction or death in patients with intra-abdominal sepsis. A discriminant analysis.
MedLine Citation:
PMID:  6849639     Owner:  NLM     Status:  MEDLINE    
One hundred and six patients found at operation to have intra-abdominal sepsis were prospectively followed up to determine the incidence of organ malfunction and death. These outcomes were correlated with age, preexisting disease, underlying cause of sepsis, shock, nutritional status, and alcoholism. Organ malfunction occurred in 31 patients (29%), 19 (61%) of whom died. Two (3%) of 75 patients without organ malfunction died. Discriminant analysis revealed a significantly increased risk of death in patients with shock at any time, age greater than 65 years, alcoholism, bowel infarction, or malnutrition. A discriminant equation based only on preoperative variables correctly assigned the outcome of death or survival in 97 (92%) of the patients based on probabilities derived from this analysis. At present, this information is primarily of interest for researchers comparing outcomes in groups of patients, but with additional refinements it may become clinically useful for individual patients.
R W Pine; M J Wertz; E S Lennard; E P Dellinger; C J Carrico; B H Minshew
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  118     ISSN:  0004-0010     ISO Abbreviation:  Arch Surg     Publication Date:  1983 Feb 
Date Detail:
Created Date:  1983-02-25     Completed Date:  1983-02-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  242-9     Citation Subset:  AIM; IM    
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MeSH Terms
Age Factors
Alcoholism / complications
Infarction / complications
Infection / complications,  diagnosis,  mortality*
Intestines / blood supply
Multiple Organ Failure / complications*
Nutrition Disorders / complications
Prospective Studies
Shock / complications
Statistics as Topic
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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