Document Detail

Determinants of neuropsychological impairment in antisocial substance abusers.
MedLine Citation:
PMID:  2248116     Owner:  NLM     Status:  MEDLINE    
Persons displaying Antisocial Personality Disorder (ASP) may be at risk for neuropsychological impairment due to a number of developmental and later life experiences to which they are prone. Thirty substance abusers meeting research criteria for ASP were compared to a demographically matched non-ASP cohort on neuropsychological test performance. The ASP subjects were found to have a higher prevalence of neuropsychological deficit. The groups were then compared on factors which might lead to brain impairment. Presence of ASP was associated with earlier and heavier past drinking patterns, more negative health and behavioral effects of alcohol abuse, and greater abuse of other drugs in addition to alcohol. The ASP alcoholics also reported a high prevalence of serious head injury (58%), although they did not differ from non-ASP alcoholics in this regard. Implications for the neuropsychology of alcoholism and for treatment are discussed.
P Malloy; N Noel; R Longabaugh; M Beattie
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Addictive behaviors     Volume:  15     ISSN:  0306-4603     ISO Abbreviation:  Addict Behav     Publication Date:  1990  
Date Detail:
Created Date:  1991-01-09     Completed Date:  1991-01-09     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7603486     Medline TA:  Addict Behav     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  431-8     Citation Subset:  IM    
Butler Hospital, Providence, RI 02809.
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MeSH Terms
Alcohol Drinking / psychology
Alcoholism / complications*,  psychology
Antisocial Personality Disorder / complications*,  psychology
Brain Damage, Chronic / diagnosis
Brain Injuries / complications
Ethanol / adverse effects*
Life Change Events
Neuropsychological Tests*
Psychiatric Status Rating Scales
Psychotropic Drugs / adverse effects
Risk Factors
Substance-Related Disorders / complications,  diagnosis*,  psychology
Grant Support
Reg. No./Substance:
0/Psychotropic Drugs; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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