Document Detail

Determinants of mortality in patients requiring prolonged intensive care unit stay after elective isolated on-pump coronary artery bypass grafting surgery.
MedLine Citation:
PMID:  20411449     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: In up to 36% of patients undergoing cardiac surgery prolonged intensive care unit stay may be necessary. Mortality rates of these patients range from 11% to 94%, causing enormous clinical and ethical issues. AIM: To identify preoperative, perioperative and postoperative risk factors of mortality in patients with prolonged intensive care unit stay after elective, isolated on-pump coronary artery bypass grafting surgery. METHODS: Clinical data of 137 patients who underwent an elective, isolated on-pump coronary artery bypass grafting operation, and had an intensive care unit stay of > or = 3 days were retrospectively evaluated. Survivors and non-survivors were compared with regard to preoperative, perioperative and postoperative characteristics to identify the risk factors for mortality. RESULTS: Multivariate analysis demonstrated that diabetes mellitus (OR = 3.62, 95% CI 1.07-12.26, p = 0.039), postoperative renal dysfunction (OR = 3.86, 95% CI 1.26-11.75, p = 0.018), postoperative intra-aortic balloon pump use (OR = 3.47; 95% CI 1.01-13.24, p = 0.048), prolonged intubation (OR = 3.90, 95% CI 1.19-12.69, p = 0.024) and re-intubation (OR = 14.83, 95% CI 4.35-50.55, p = 0.001) were significant and independent risk factors of mortality. CONCLUSION: The present study found that the preoperative presence of diabetes mellitus, and postoperative multiorgan failure syndrome decreased the probability of survival in patients with prolonged intensive care unit stay after elective isolated on-pump coronary artery bypass surgery.
Hayrettin Tekumit; Kemal Uzun; Ali Riza Cenal; Cenk Tataroglu; Adil Polat; Esat Akinci
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Kardiologia polska     Volume:  68     ISSN:  0022-9032     ISO Abbreviation:  Kardiol Pol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-22     Completed Date:  2010-07-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376352     Medline TA:  Kardiol Pol     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  257-62     Citation Subset:  IM    
Ozel Avrupa Safak Hastanesi, Kucukkoy yolu hamam sok., Turkey.
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MeSH Terms
Coronary Artery Bypass / mortality*
Diabetes Mellitus / epidemiology
Intensive Care / statistics & numerical data*
Intubation, Intratracheal / statistics & numerical data
Kidney Diseases / epidemiology
Length of Stay / statistics & numerical data*
Middle Aged
Multiple Organ Failure / epidemiology
Multivariate Analysis
Postoperative Complications / epidemiology
Retrospective Studies
Risk Factors
Surgical Procedures, Elective / mortality*
Survival Rate
Turkey / epidemiology
Comment In:
Kardiol Pol. 2010 Mar;68(3):263-4   [PMID:  20491176 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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