Document Detail


Determinants of indoor allergens in tropical child care centers.
MedLine Citation:
PMID:  18208465     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Limited data are available about indoor allergen determinants in child care centers (CCCs) especially in the tropics. This information is important epidemiologically and clinically considering many children attend CCCs. The purpose of this study was to determine the allergen concentrations in CCCs and their associations with CCC characteristics and indoor air quality (IAQ). A panel of indoor allergens including Der p 1, Blo t 5, Fel d 1, Can f 1, Mus m 1, Bla g 1 and Asp f 1 were evaluated from dusts vacuumed from classroom floors of CCCs. Allergen levels were assayed with antibody-based bioplex array or enzyme-linked immunosorbent assays. Indoor temperature, relative humidity and air exchange rates were measured and CCC characteristics inspected. Allergen levels were linearly regressed with CCC characteristics and IAQ. The dominant allergens found in classroom floors were Der p 1, Blo t 5 and Fel d 1. Lower indoor temperatures were associated with higher Der p 1 while lower ventilation rates were associated with higher Blo t 5 concentrations. Prevalence of cat owners was found to be a predictor for Fel d 1 concentrations. Full or partial carpeting is associated with higher dust mite allergen levels. These findings provide information for future indoor allergen exposure assessment studies in CCCs and can be used for intervention with regard to allergen avoidance.
Authors:
Mohamed Sultan Zuraimi; Tan Ching Ong; Kwok Wai Tham; Fook Tim Chew
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-01-12
Journal Detail:
Title:  Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology     Volume:  19     ISSN:  1399-3038     ISO Abbreviation:  Pediatr Allergy Immunol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-16     Completed Date:  2009-05-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106718     Medline TA:  Pediatr Allergy Immunol     Country:  England    
Other Details:
Languages:  eng     Pagination:  746-55     Citation Subset:  IM    
Affiliation:
Department of Building, School of Design and Environment, National University of Singapore, Singapore. bdgzms@nus.edu.sg
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MeSH Terms
Descriptor/Qualifier:
Allergens / analysis*,  immunology
Child
Child Day Care Centers*
Dust / analysis*,  immunology
Floors and Floorcoverings
Humans
Humidity
Hypersensitivity / epidemiology*
Singapore
Temperature
Tropical Climate*
Ventilation
Chemical
Reg. No./Substance:
0/Allergens; 0/Dust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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