Document Detail

Determinants of food allergy.
MedLine Citation:
PMID:  22244230     Owner:  NLM     Status:  MEDLINE    
Food allergy is an emerging epidemic in the United States and the Western world. The determination of factors that make certain foods allergenic is still not clearly understood. Only a tiny fraction of thousands of proteins and other molecules is responsible for inducing food allergy. In this review, the authors present 3 examples of food allergies with disparate clinical presentations: peanut, soy, and mammalian meat. The potential relationships between allergen structure and function, emphasizing the importance of cross-reactive determinants, immunoglobulin E antibodies to the oligosaccharides, and the immune responses induced in humans are discussed.
Madhan Masilamani; Scott Commins; Wayne Shreffler
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Immunology and allergy clinics of North America     Volume:  32     ISSN:  1557-8607     ISO Abbreviation:  Immunol Allergy Clin North Am     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-01-16     Completed Date:  2012-06-28     Revised Date:  2014-03-28    
Medline Journal Info:
Nlm Unique ID:  8805635     Medline TA:  Immunol Allergy Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  11-33     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
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MeSH Terms
Allergens / ultrastructure
Food Hypersensitivity / immunology*,  physiopathology*
Immunoglobulin E / immunology
Meat / adverse effects
Peanut Hypersensitivity
Plants / adverse effects,  immunology
Soy Foods / adverse effects
Grant Support
K08 AI085190/AI/NIAID NIH HHS; K08 AI085190-03/AI/NIAID NIH HHS; L30 AI080151/AI/NIAID NIH HHS; L30 AI080151-03/AI/NIAID NIH HHS
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E

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