| Determinants and consequences of discrepancies in menstrual and ultrasonographic gestational age estimates. | |
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MedLine Citation:
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PMID: 15663577 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To assess the association between maternal and fetal characteristics and discrepancy between last normal menstrual period and early (<20 weeks) ultrasound-based gestational age and the association between discrepancies and pregnancy outcomes. DESIGN: Hospital-based cohort study. SETTING: Montreal, Canada. SAMPLE: A total of 46,514 women with both menstrual- and early ultrasound-based gestational age estimates. MAIN OUTCOME MEASURES: Positive (last normal menstrual period > early ultrasound, i.e. menstrual-based gestational age is higher than early ultrasound-based gestational age, so that the expected date of delivery is earlier with the menstrual-based gestational age) discrepancies > or =+7 days, mean birthweight, low birthweight, stillbirth and in-hospital neonatal death. RESULTS: Multiparous mothers and those with diabetes, small stature or high pre-pregnancy body mass index were more likely to have positive discrepancies. The proportion of women with discrepancies > or =+7 days was significantly higher among chromosomally malformed and female fetuses. The mean birthweight declined with increasingly positive differences. The risk of low birthweight was significantly higher for positive differences. Associations with fetal growth measures were more plausible with early ultrasound estimates. CONCLUSIONS: Although most discrepancies between last normal menstrual period- and early ultrasound-based gestational age are attributable to errors in menstrual dating, our results suggest that some positive differences reflect early growth restriction. |
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Authors:
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Isabelle Morin; Lucie Morin; Xun Zhang; Robert W Platt; Béatrice Blondel; Gérard Bréart; Robert Usher; Michael S Kramer |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 112 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2005 Feb |
Date Detail:
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Created Date: 2005-01-24 Completed Date: 2005-02-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 145-52 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, McGill University Faculty of Medicine, Montreal, Quebec, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cohort Studies Female Gestational Age* Humans Infant, Low Birth Weight / physiology Infant, Newborn Infant, Small for Gestational Age / physiology Menstruation* Multivariate Analysis Pregnancy Risk Factors Time Factors Ultrasonography, Prenatal / standards* |
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