Document Detail

Detection of specific IgE to human milk proteins in sera of atopic infants.
MedLine Citation:
PMID:  9276457     Owner:  NLM     Status:  MEDLINE    
Specific IgE (sIgE) for cow's milk proteins (CMP) have been reported to be present in blood sera of exclusively breast-fed infants. The aim of this study was to find whether the presence of sIgE to human milk proteins in the sera of exclusively breast-fed infants could explain the apparent detection of sIgE to CMP in infants that were never previously in contact with cow's milk. sIgE for human milk whey proteins were found in the blood sera of atopic infants, and these sIgE strongly cross-reacted with the corresponding CMP. In none of the sera examined were sIgE to bovine beta-lactoglobulin detected.
A Cantisani; M G Giuffrida; C Fabris; E Bertino; A Coscia; R Oggero; G Monti; P Stroppiana; A Conti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  FEBS letters     Volume:  412     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-09-11     Completed Date:  1997-09-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  515-7     Citation Subset:  IM    
Centro Studio Alimentazione Animali, CNR, Torino, Italy.
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MeSH Terms
Antibody Specificity*
Binding Sites, Antibody
Binding, Competitive / immunology
Cattle / immunology
Electrophoresis, Polyacrylamide Gel
Hypersensitivity, Immediate / blood,  etiology,  immunology*
Immunoglobulin E / blood*,  metabolism
Milk Proteins / immunology*,  metabolism
Milk, Human / immunology*
Species Specificity
Reg. No./Substance:
0/Binding Sites, Antibody; 0/Milk Proteins; 37341-29-0/Immunoglobulin E

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